- RNA Modifications Modulate Activation of Innate Toll-Like Receptors
2019/01/29 by Isabel Freund, Tatjana Eigenbrod, Mark Helm +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #RNA modifications and cancer #interferon and immune responses #Immune Response and Inflammation #RNA #Biology #TLR7 #Innate immune system #Context (archaeology) #Pattern recognition receptor #Receptor #Immune system #Toll-like receptor #Cell biology #Computational biology #Genetics #Gene
- Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis
2014/04/23 by Milka Koupenova, Olga Vitseva, Christopher R. MacKay +7 · 30 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Immune system #Immunology #Inflammasome and immune disorders #Inflammatory Biomarkers in Disease Prognosis #Innate immune system #Internal medicine #Medicine #Platelet #Platelet Disorders and Treatments #Platelet activation #TLR7 #Thrombosis #Toll-like receptor
- Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer
2009/06/01 by Luke O'neill, Luke A.J. O’Neill, Clare E. Bryant +3 · 28 citations
Immunology and Microbiology · Medicine · #Biology #Cancer #Cancer research #Gene #Genetics #Immune Cell Function and Interaction #Immune Response and Inflammation #Immune system #Immunology #Inflammation #Innate immune system #Interferon regulatory factors #Medicine #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Receptor #TLR2 #TLR4 #TLR7 #TRIF #Toll-like receptor #Transcription factor #Tumor necrosis factor alpha
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
2009/04/21 by Leslie van der Fits, Sabine Mourits, Jane S.A. Voerman +13 · 45 citations
Immunology and Microbiology · Medicine · #Autoimmune Bullous Skin Diseases #Biology #CD11c #Imiquimod #Immune system #Immunodeficiency and Autoimmune Disorders #Immunology #Inflammation #Innate immune system #Interleukin 17 #Interleukin 23 #Medicine #Psoriasis #Psoriasis: Treatment and Pathogenesis #TLR7 #Toll-like receptor