- Oral renin inhibitors
2006/09/28 by Jan A Staessen, Jan A. Staessen, Yan Li +2 · 215 citations
Medicine · #Aliskiren #Bioavailability #Blood pressure #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Hormonal Regulation and Hypertension #Internal medicine #Medicine #Oral administration #Orally active #Pharmacodynamics #Pharmacokinetics #Pharmacology #Plasma renin activity #Renin inhibitor #Renin-Angiotensin System Studies #Renin–angiotensin system
- Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin
2000/07/01 by J Rahuel, Joseph Rahuel, Vittorio Rasetti +18 · 287 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Bioinformatics #Biology #Computational biology #Drug #Drug discovery #Neuropeptides and Animal Physiology #Oral administration #Orally active #Pharmacology #Protein Hydrolysis and Bioactive Peptides #Renin-Angiotensin System Studies