Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism

2006/10/10 by John P. Incardona, Heather L. Day, Tracy K. Collier +1 · 1 citation
Environmental Science · #Toxic Organic Pollutants Impact #Effects and risks of endocrine disrupting chemicals #Environmental Toxicology and Ecotoxicology

paper · doi:10.1016/j.taap.2006.09.018

Citations

• Relative Contributions of Affinity and Intrinsic Efficacy to Aryl Hydrocarbon Receptor Ligand Potency
• Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons

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• Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development