Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development

2011/09/20 by John P. Incardona, Tiffany L. Linbo, Nathaniel L. Scholz
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Zebrafish Biomedical Research Applications #Environmental Toxicology and Ecotoxicology #Toxic Organic Pollutants Impact

paper · doi:10.1016/j.taap.2011.09.010

Citations

• Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism
• Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons