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The computational role of structure in neural activity and connectivity

2023/08/31 by Srdjan Ostojic, Stefano Fusi, Ostojic, Srdjan +1 · 2 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neural dynamics and brain function #Functional Brain Connectivity Studies #Advanced Fluorescence Microscopy Techniques

paper · pdf · doi:10.48550/arxiv.2308.16772

Abstract

One major challenge of neuroscience is finding interesting structures in a seemingly disorganized neural activity. Often these structures have computational implications that help to understand the functional role of a particular brain area. Here we outline a unified approach to characterize these structures by inspecting the representational geometry and the modularity properties of the recorded activity, and show that this approach can also reveal structures in connectivity. We start by setting up a general framework for determining geometry and modularity in activity and connectivity and relating these properties with computations performed by the network. We then use this framework to review the types of structure found in recent works on model networks performing three classes of computations.

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