17α-ethinyl estradiol attenuates depressive-like behavior through GABAA receptor activation/nitrergic pathway blockade in ovariectomized mice

2016/02/16 by Seyed Soheil Saeedi Saravi, Alireza Arefidoust, Rahele Yaftian +2
Medicine · Neuroscience · #Menopause: Health Impacts and Treatments #Stress Responses and Cortisol #Nerve injury and regeneration

paper · doi:10.1007/s00213-016-4242-9

Citations

• Nitric oxide synthase inhibitors have antidepressant-like properties in mice
• NO as a signalling molecule in the nervous system
• Estradiol reduces depressive-like behavior through inhibiting nitric oxide/cyclic GMP pathway in ovariectomized mice