Claudins and the Modulation of Tight Junction Permeability

2013/04/01 by Dorothee Günzel, Alan S. L. Yu, Alan S.L. Yu · 13 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Barrier Structure and Function Studies #Connexins and lens biology #Cancer-related molecular mechanisms research

paper · doi:10.1152/physrev.00019.2012

Abstract

Claudins are tight junction membrane proteins that are expressed in epithelia and endothelia and form paracellular barriers and pores that determine tight junction permeability. This review summarizes our current knowledge of this large protein family and discusses recent advances in our understanding of their structure and physiological functions.

Citations

• Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells
• Phenomenological Theory of Ion Solvation. Effective Radii of Hydrated Ions

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