Kynurenine pathway metabolism and the microbiota-gut-brain axis

2016/07/06 by P.J. Kennedy, Paul J. Kennedy, John F. Cryan +4 · 11 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · Psychology · #Tryptophan and brain disorders #Gut microbiota and health #Neuroendocrine regulation and behavior

paper · doi:10.1016/j.neuropharm.2016.07.002

Citations

• The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders
• An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid
• Antimicrobial activity of psychotropic drugs
• Adult Hippocampal Neurogenesis Is Regulated by the Microbiome
• Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticusR0052 andBifidobacterium longumR0175) in rats and human subjects
• Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
• Diet-induced extinctions in the gut microbiota compound over generations

Cited by

• The Microbiota-Gut-Brain Axis
• The Emerging Short Chain Fatty Acid Enriched Metabotype in Irritable Bowel Syndrome and Its Potential Clinical Relevance
• Distinguishing the causative, correlative and bidirectional roles of the gut microbiota in mental health
• Brain–Gut Axis
• The architecture of gut microecological networks and the governance of host metabolic homeostasis
• NLRP3 inflammasome-driven pathways in depression: Clinical and preclinical findings
• Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management
• Gut microbiome-mediated epigenetic regulation of brain disorder and application of machine learning for multi-omics data analysis
• Indole induces anxiety-like behaviour in mice mediated by brainstem locus coeruleus activation
• Impact of intestinal disorders on central and peripheral nervous system diseases
• Microbiota-Gut-Brain Axis: New Therapeutic Opportunities