Probing the Molecular Mechanism of Interaction between 4-n-Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist

2005/10/06 by Christopher J. Langmead, Victoria A. H. Fry, Victoria AH. Fry +6
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Receptor Mechanisms and Signaling #Neuroscience and Neuropharmacology Research #Protein Kinase Regulation and GTPase Signaling

paper · doi:10.1124/mol.105.017814

Citations

• Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
• Systematic risk behavior of financially distressed firms