Probe Dependence in the Allosteric Modulation of a G Protein-Coupled Receptor: Implications for Detection and Validation of Allosteric Ligand Effects

2011/10/12 by Celine Valant, Céline Valant, Christian C. Felder +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · Pharmacology, Toxicology and Pharmaceutics · #Receptor Mechanisms and Signaling #Neuropeptides and Animal Physiology #Pharmacogenetics and Drug Metabolism

paper · doi:10.1124/mol.111.074872

Citations

• Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

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