2010/01/02 by Goutam Chandra, Kalyan Ghosh, Chandra, Goutam +5
Biochemistry, Genetics and Molecular Biology · Materials Science · Medicine · #Biological Physics (physics.bio-ph) #FOS: Physical sciences #Gold and Silver Nanoparticles Synthesis and Applications #Iron Metabolism and Disorders #Protein Interaction Studies and Fluorescence Analysis
paper · pdf · doi:10.48550/arxiv.1001.0284
openalex publication_date 2010/01/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
In this article, we discuss metal-protein interactions in the Ag-lysozyme\ncomplex by spectroscopic measurements. The analysis of the variation in\nrelative intensities of SERS bands reveal the orientation and the change in\nconformation of the protein molecules on the Ag surface with time. The\ninteraction kinetics of metal-protein complexes has been analyzed over a period\nof three hours via both Raman and absorption measurements. Our analysis\nindicates that the Ag nanoparticles most likely interact with Trp-123 which is\nin close proximity to Phe-34 of the lysozyme molecule.\n