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Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms

2007/03/21 by Antonia Nostro, Andrea Sudano Roccaro, Giuseppe Bisignano +9 · 553 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Advanced Chemical Sensor Technologies #Antimicrobial #Bacteria #Bacterial biofilms and quorum sensing #Biofilm #Biology #Carvacrol #Chemistry #Essential Oils and Antimicrobial Activity #Essential oil #Food science #Microbiology #Minimum inhibitory concentration #Staphylococcus aureus #Staphylococcus epidermidis #Thymol

paper · doi:10.1099/jmm.0.46804-0

published in Journal of Medical Microbiology 56(4), 519-523 (Microbiology Society)

openalex publication_date 2007/03/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as the effects of the oils on biofilm formation. For most of the S. aureus (n=6) and S. epidermidis (n=6) strains tested, the biofilm inhibitory concentration (0.125-0.500 %, v/v, for oregano, and 0.031-0.125 %, v/v, for carvacrol and thymol) and biofilm eradication concentration (0.25-1.0 %, v/v, for oregano and 0.125-0.500 %, v/v, for carvacrol and thymol) values were twofold or fourfold greater than the concentration required to inhibit planktonic growth. Subinhibitory concentrations of the oils attenuated biofilm formation of S. aureus and S. epidermidis strains on polystyrene microtitre plates.

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