Correlations between Molecular Mobility and Chemical Stability During Storage of Amorphous Pharmaceuticals

2007/04/24 by Sumie Yoshioka, Yukio Aso · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Drug Solubulity and Delivery Systems #Protein purification and stability #Microencapsulation and Drying Processes

paper · doi:10.1002/jps.20926

Citations

• Solid‐state chemical stability of proteins and peptides
• Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
• A Solid-State NMR Study of Protein Mobility in Lyophilized Protein–Sugar Powders
• How Does Residual Water Affect the Solid-state Degradation of Drugs in the Amorphous State?
• Solid‐Phase Aggregation of Proteins under Pharmaceutically Relevant Conditions†

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