Reaction of enol silyl ethers and enol acetates with copper(II) nitrate-iodine: synthesis of .alpha.-iodo ketones

1991/11/01 by Antonella Dalla Cort · 35 citations
Chemistry · #Alpha (finance) #Catalysis #Chemistry #Copper #Enol #Enol ether #Iodine #Medicinal chemistry #Organic chemistry #Oxidative Organic Chemistry Reactions #Silylation

paper · doi:10.1021/jo00023a042

published in The Journal of Organic Chemistry 56(23), 6708-6709 (American Chemical Society)

openalex publication_date 1991/11/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

A new and convenient procedure for the prepn. of α-iodo ketones from the corresponding enol silyl ether or enol acetate with I2 and copper(II) nitrate in CH3CN is reported. The method shows wide applicability and very good yields (85-100%).

Cited by

• Formation of Carbon–Halogen Bonds ( Cl , Br , I )

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