Comparative Physiology of Nociception and Pain

2017/12/06 by Lynne U. Sneddon · 1 voice · 242 citations
Medicine · Neuroscience · Psychology · #Internal medicine #Ion Channels and Receptors #Medicine #Neuroscience #Nociception #Nociceptor #Olfactory and Sensory Function Studies #Pain Mechanisms and Treatments #Psychology #Receptor

paper · doi:10.1152/physiol.00022.2017

published in Physiology 33(1), 63-73 (American Physiological Society)

openalex publication_date 2017/12/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

The study of diverse animal groups allows us to discern the evolution of the neurobiology of nociception. Nociception functions as an important alarm system alerting the individual to potential and actual tissue damage. All animals possess nociceptors, and, in some animal groups, it has been demonstrated that there are consistent physiological mechanisms underpinning the nociceptive system. This review considers the comparative biology of nociception and pain from an evolutionary perspective.

Citations

• Mechanosensory Neurons InnervatingAplysiaSiphon Encode Noxious Stimuli and Display Nociceptive Sensitization
• Nociceptors—Noxious Stimulus Detectors
• Thermal avoidance in Caenorhabditis elegans : An approach to the study of nociception
• Nociceptive Neurons Protect Drosophila Larvae from Parasitoid Wasps
• Pain Mechanisms: A New Theory
• Specification of the nervous system
• Neuroma formation and abnormal afferent nerve discharges after partial beak amputation (beak trimming) in poultry
• Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms
• The neurobiology of skeletal pain
• Nociceptors: the sensors of the pain pathway
• Nociceptors: a phylogenetic view
• painless, a Drosophila Gene Essential for Nociception

Cited by

• Evolution of nociception and pain: evidence from fish models

Discussions

• [CW: Animal Cruelty] 370 billion crickets are farmed for food every year. Scientists have discovered they may feel pain [lemmy, 90 points, 64 comments]