2014/11/06 by Duane J. Funk, Anand Kumar · 1 citation
Medicine · Health Professions · #Viral Infections and Outbreaks Research #Disaster Response and Management #Infection Control and Ventilation #Medicine #Ebola virus #Intensive care medicine #Disease #Epidemiology #Personal protective equipment #Outbreak #Coronavirus disease 2019 (COVID-19) #Infectious disease (medical specialty) #Virology #Internal medicine
paper · pdf · doi:10.1007/s12630-014-0257-z
openalex publication_date 2014/11/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
PURPOSE: Ebola virus disease (EVD) is a viral hemorrhagic fever that is highly transmissible and all too often rapidly fatal. Recent outbreaks in West Africa reveal that this infection has the potential to be transmitted worldwide. Anesthesiologists and intensivists, due to their training in the management of the critically ill, may be called upon to assist in the management of these patients. The focus of this brief review is on the epidemiology, pathogenesis, and management of patients with EVD. SOURCE: Review of the current literature. PRINCIPAL FINDINGS: Ebola virus disease causes severe diarrhea, electrolyte disturbances and other major end-organ dysfunction. Early aggressive resuscitation may reduce the mortality of this disease. There is presently no available vaccine nor cure, with experimental therapies having yielded limited success. Personal protective equipment (PPE) is necessary for all patient contact, and enhanced PPE is required for all aerosol-generating medical procedures. CONCLUSION: Anesthesiologists and intensivists may be called upon to manage patients with EVD. It is important that these clinicians have an appreciation for the epidemiology and pathogenesis of this disease and for the proper utilization of PPE when treating these patients.