Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

2013/06/09 by Christopher B. Ford, Christopher B Ford, Rupal Shah +14 · 438 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Antibiotics #Biology #Drug resistance #Gene #Genetics #Lineage (genetic) #Medicine #Microbiology #Mutation #Mutation rate #Mycobacterium research and diagnosis #Mycobacterium tuberculosis #Pathology #Tuberculosis #Tuberculosis Research and Epidemiology #Virology

paper · open access · doi:10.1038/ng.2656

published in Nature Genetics 45(7), 784-790 (Springer Science and Business Media LLC)

crossref issued 2013/06/09 · crossref published 2013/06/09 · crossref published-online 2013/06/09 · openalex publication_date 2013/06/09 · crossref created 2013/06/09 · crossref published-print 2013/07/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/07/29 · openalex updated_date 2026/08/06

Citations

• On the rate of molecular evolution
• Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes
• The Competitive Cost of Antibiotic Resistance in Mycobacterium tuberculosis
• Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak
• A new look at the statistical model identification
• Multimodel Inference
• MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

Cited by

• Totally drug‐resistant tuberculosis and adjunct therapies
• Multidrug-resistant tuberculosis [wikipedia]