Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin

2015/04/09 by Marco Demaria, Pierre Yves Desprez, Pierre Y. Desprez +2 · 27 citations
Medicine · Neuroscience · #Telomeres, Telomerase, and Senescence #Circadian rhythm and melatonin #Skin Protection and Aging

paper · pdf · doi:10.1038/jid.2015.108

Citations

• Decreased Collagen Production in Chronologically Aged Skin
• Factors Affecting Wound Healing

Cited by

• Endocrine Controls of Skin Aging
• Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging
• MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. [europepmc]
• The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging. [europepmc]
• Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. [europepmc]
• Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses? [europepmc]
• Senescent cells: an emerging target for diseases of ageing. [europepmc]
• Effect of Orally Administered Collagen Peptides from Bovine Bone on Skin Aging in Chronologically Aged Mice. [europepmc]
• Senescence and tumor suppression. [europepmc]
• Systemic clearance of p16 INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration. [europepmc]
• Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D. [europepmc]
• Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age. [europepmc]
• Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype. [europepmc]
• Skin Structure-Function Relationships and the Wound Healing Response to Intrinsic Aging. [europepmc]
• tBHP treatment as a model for cellular senescence and pollution-induced skin aging. [europepmc]
• On the evolution of cellular senescence. [europepmc]
• Finding Solutions for Fibrosis: Understanding the Innate Mechanisms Used by Super-Regenerator Vertebrates to Combat Scarring. [europepmc]
• How good is the evidence that cellular senescence causes skin ageing? [europepmc]
• Structural and Functional Changes and Possible Molecular Mechanisms in Aged Skin. [europepmc]
• Microbiome and Human Aging: Probiotic and Prebiotic Potentials in Longevity, Skin Health and Cellular Senescence. [europepmc]
• Tissue engineering strategies to bioengineer the ageing skin phenotype in vitro. [europepmc]
• Elevated skin senescence in young mice causes delayed wound healing. [europepmc]
• Cellular Senescence in Acute and Chronic Wound Repair. [europepmc]
• Fibroblast heterogeneity: Keystone of tissue homeostasis and pathology in inflammation and ageing. [europepmc]
• Dermal Fibroblasts as the Main Target for Skin Anti-Age Correction Using a Combination of Regenerative Medicine Methods. [europepmc]
• Anti-Aging Activity and Modes of Action of Compounds from Natural Food Sources. [europepmc]
• Cellular senescence and wound healing in aged and diabetic skin. [europepmc]