2010/01/01 by Elizabeth J. Paik, Leonard I. Zon · 184 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Aquaculture disease management and microbiota #Biology #Cell biology #Computational biology #Danio #Epigenetics and DNA Methylation #Gene #Genetics #Haematopoiesis #Model organism #Model system #Stem cell #Zebrafish #Zebrafish Biomedical Research Applications
paper · pdf · doi:10.1387/ijdb.093042ep
published in The International Journal of Developmental Biology 54(6-7), 1127-1137 (University of the Basque Country)
crossref issued 2010/01/01 · crossref published 2010/01/01 · crossref published-print 2010/01/01 · openalex publication_date 2010/01/01 · crossref created 2010/08/16 · crossref deposited 2025/01/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31 · crossref indexed 2026/08/04
The model organism Danio rerio, also known as the zebrafish, is an excellent system for studying the developmental process of hematopoiesis. It is an ideal model for in vivo imaging, and it is useful for large-scale genetic screens. These have led to the discovery of previously unknown players in hematopoiesis, as well as helped our understanding of hematopoietic development. In this review, we will summarize hematopoiesis in the zebrafish and discuss how genetic approaches using the zebrafish system have helped to build our current knowledge in the field of hematopoiesis.