Crossing the Borders: the amino acid transporter LAT1 (SLC7A5) in the Blood-Brain Barrier

2025/12/01 by Mariafrancesca Scalise, Raffaella Scanga, Lara Console +5

paper · doi:10.1016/j.neuint.2025.106070

crossref created 2025/10/08 · crossref issued 2025/12/01 · crossref published 2025/12/01 · crossref published-print 2025/12/01 · crossref deposited 2026/03/18 · crossref indexed 2026/08/05

Citations

• Glut1 Deficiency Syndrome: Novel Pathomechanisms, Current Concepts, and Challenges
• A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
• First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors
• Blood-Brain Barrier: From Physiology to Disease and Back
• The SLC3 and SLC7 families of amino acid transporters
• Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria
• Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors
• Structure and function of the blood–brain barrier