2024/01/28 by Yuzhuo Liu, Zhenzhen Zhu, Wei Lv
Dentistry · Medicine · #Adenocarcinoma #Biopsy #Cancer #Cancer Diagnosis and Treatment #Infratemporal fossa #Internal medicine #Lung Cancer Diagnosis and Treatment #Medicine #Metastasis #Oral and Maxillofacial Pathology #Orbit (dynamics) #Pathology #Radiology #Skull #Surgery #Temporomandibular joint
paper · pdf · doi:10.1177/01455613231218139
crossref issued 2024/01/28 · crossref published 2024/01/28 · crossref published-online 2024/01/28 · openalex publication_date 2024/01/28 · crossref created 2024/01/29 · openalex created_date 2025/10/10 · crossref deposited 2026/08/05 · crossref indexed 2026/08/05 · openalex updated_date 2026/08/06
Neoplasms in the infratemporal fossa (ITF) are rare and insidious lesions that cause various symptoms due to involvement of the temporomandibular joint (TMJ), paranasal sinuses, and orbit. Here, we report a case of metastatic non-small cell lung adenocarcinoma in the ITF. The patient presented with facial pain and limited mouth opening, which did not respond to treatment for TMJ disorder, and a neoplasm was discovered in the ITF through medical imaging. With an open biopsy, the diagnosis was finalized. This report suggested that the physician should consider lesions in the ITF when facial pain and limited mouth opening failed local treatment, and distant metastasis of malignant tumor should be alerted. We also reviewed the literature regarding metastatic cancer to the ITF.