Assignment of the human α-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization

2008/05/16 by Steve D. Wilton, L. Lim, S.D. Dorosz +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Genomic variations and chromosomal abnormalities #RNA modifications and cancer #Tropomyosin #Biology #Fluorescence in situ hybridization #Metaphase #Molecular biology #Genetics #Somatic cell #Gene #Chromosome #Gene mapping #In situ hybridization #Gene expression #Actin

paper · doi:10.1159/000134206

openalex publication_date 2008/05/16 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/22

Abstract

Sequence-tagged sites (STSs) were developed for the human alpha-tropomyosin gene TPM4. One STS was used to amplify DNA from somatic cell hybrids to localize TPM4 to chromosome 19. The other, a product from a long-range PCR, was used directly as a probe to refine the localization of TPM4 to 19p13.1 by fluorescence in situ hybridization to metaphase chromosome spreads.

Cited by

• Tropomyosin-Based Regulation of the Actin Cytoskeleton in Time and Space
• Tropomyosin [wikipedia]

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