Large-scale de novo DNA synthesis: technologies and applications

2014/04/29 by Sriram Kosuri, George M. Church, George M Church · 3 citations
Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #Biology #CRISPR and Genetic Engineering #Computational biology #Computer science #DNA #DNA synthesis #Genetics #Materials science #Nanotechnology #Physics #RNA and protein synthesis mechanisms #Scale (ratio) #Synthetic biology

paper · pdf · doi:10.1038/nmeth.2918

crossref issued 2014/04/29 · crossref published 2014/04/29 · crossref published-online 2014/04/29 · openalex publication_date 2014/04/29 · crossref created 2014/04/29 · crossref published-print 2014/05/01 · crossref deposited 2024/12/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29 · crossref indexed 2026/08/04

Citations

• Neural network computation with DNA strand displacement cascades
• Accurate gene synthesis with tag-directed retrieval of sequence-verified DNA molecules
• Next-Generation Digital Information Storage in DNA
• Chemical Synthesis of Poliovirus cDNA: Generation of Infectious Virus in the Absence of Natural Template
• High-density oligonucleotide arrays
• The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
• Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus
• Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides
• Light-Directed, Spatially Addressable Parallel Chemical Synthesis

Cited by

• Robust Chemical Preservation of Digital Information on DNA in Silica with Error‐Correcting Codes
• Constrained Error-Correcting Codes for Efficient DNA Synthesis
• Leroy Hood [wikipedia]