2016/03/04 by Jomar F. Rabajante, Jerrold M. Tubay, Hiromu Ito +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Computer Science · #Evolution and Genetic Dynamics #Mathematical and Theoretical Epidemiology and Ecology Models #Nonlinear Dynamics and Pattern Formation #Genotype #Dynamics (music) #Host (biology) #Biology #Parasite hosting #Queen (butterfly) #Rest (music) #Genetics #Zoology #Gene #Medicine #Computer science #Hymenoptera #Physics
paper · pdf · doi:10.1126/sciadv.1501548
openalex publication_date 2016/03/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22
Interactions between hosts and parasites have been hypothesized to cause winnerless coevolution, called Red Queen dynamics. The canonical Red Queen dynamics assume that all interacting genotypes of hosts and parasites undergo cyclic changes in abundance through negative frequency-dependent selection, which means that any genotype could become frequent at some stage. However, this prediction cannot explain why many rare genotypes stay rare in natural host-parasite systems. To investigate this, we build a mathematical model involving multihost and multiparasite genotypes. In a deterministic and controlled environment, Red Queen dynamics occur between two genotypes undergoing cyclic dominance changes, whereas the rest of the genotypes remain subordinate for long periods of time in phase-locked synchronized dynamics with low amplitude. However, introduction of stochastic noise in the model might allow the subordinate cyclic host and parasite types to replace dominant cyclic types as new players in the Red Queen dynamics. The factors that influence such evolutionary switching are interhost competition, specificity of parasitism, and degree of stochastic noise. Our model can explain, for the first time, the persistence of rare, hardly cycling genotypes in populations (for example, marine microbial communities) undergoing host-parasite coevolution.