Down syndrome: a cardiovascular perspective

2009/02/18 by J. C. Vis, M. G. J. Duffels, Michiel M. Winter +4 · 185 citations
Medicine · #Down syndrome and intellectual disability research #Congenital Heart Disease Studies #Cardiac Structural Anomalies and Repair #Down syndrome #Medicine #Epidemiology #Internal medicine #Intensive care medicine #Pediatrics #Cardiology #Psychiatry

paper · doi:10.1111/j.1365-2788.2009.01158.x

published in Journal of Intellectual Disability Research 53(5), 419-425 (Wiley)

openalex publication_date 2009/02/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

This review focuses on the heart and vascular system in patients with Down syndrome. A clear knowledge on the wide spectrum of various abnormalities associated with this syndrome is essential for skillful management of cardiac problems in patients with Down syndrome. Epidemiology of congenital heart defects, cardiovascular aspects and thyroid-related cardiac impairment in patients with Down syndrome will be discussed.

Citations

• Down's syndrome
• Classification of Human Chromosome 21 Gene-Expression Variations in Down Syndrome: Impact on Disease Phenotypes
• Health Supervision for Children With Down Syndrome

Cited by

• Down syndrome: searching for the genetic culprits
• Atrial septal defect [wikipedia]

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