2020/01/09 by Maria Abbattista, Marco Capecchi, Ida Martinelli · 34 citations
Medicine · #Venous Thromboembolism Diagnosis and Management #Vascular anomalies and interventions #Blood Coagulation and Thrombosis Mechanisms #Medicine #Venous thrombosis #Thrombosis #Surgery #Intensive care medicine
paper · pdf · doi:10.1182/blood.2019000918
published in Blood 135(5), 326-334 (Elsevier BV)
openalex publication_date 2020/01/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Venous thrombosis rarely occurs at unusual sites such as cerebral, splanchnic, upper-extremity, renal, ovarian, or retinal veins. Clinical features, symptoms, and risk factors of rare thrombotic manifestations are heterogeneous and in large part differ from those typical of the commonest manifestations of venous thrombosis at the lower extremities. The therapeutic approach also varies widely according to the affected site, whether cerebral, abdominal, or extraabdominal. To date, anticoagulant therapy for thrombosis at unusual sites is generally accepted, but the optimal therapeutic approach remains challenging. This review is focused on the treatment of unusual thrombotic manifestations as reported in the most recent guidelines and according to the updated scientific literature.