Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

2009/07/01 by Shaun Purcell, Jennifer Stone, Pamela Sklar +71 · 14 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Biology #Bipolar disorder #Cognition #Gene #Genetic Associations and Epidemiology #Genetics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases #Genotype #Polygenic risk score #Psychiatry #Psychology #Schizophrenia (object-oriented programming) #Single-nucleotide polymorphism #Variation (astronomy)

paper · doi:10.1038/nature08185

crossref issued 2009/07/01 · crossref published 2009/07/01 · crossref published-online 2009/07/01 · openalex publication_date 2009/07/01 · crossref created 2009/07/01 · crossref published-print 2009/08/01 · openalex created_date 2016/06/24 · crossref deposited 2023/05/18 · openalex updated_date 2026/08/04 · crossref indexed 2026/08/04

Citations

• PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
• XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance.

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• Understanding Heritability: What it is and What it is Not
• Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
• Genetics and educational attainment
• Genetic Classification of Populations Using Supervised Learning
• Uncovering the Hidden Risk Architecture of the Schizophrenias: Confirmation in Three Independent Genome-Wide Association Studies
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
• Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders
• Paul E. Meehl [wikipedia]
• Schizoaffective disorder [wikipedia]