Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

2012/02/19 by Sang Lee, S Hong Lee, Teresa R DeCandia +12 · 8 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Biology #Computational biology #Evolutionary biology #Gene #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals #Genetic variation #Genetics #Genomic variations and chromosomal abnormalities #Genotype #Psychiatry #Psychology #Schizophrenia (object-oriented programming) #Single-nucleotide polymorphism #Variation (astronomy)

paper · doi:10.1038/ng.1108

crossref issued 2012/02/19 · crossref published 2012/02/19 · crossref published-online 2012/02/19 · openalex publication_date 2012/02/19 · crossref created 2012/02/19 · crossref published-print 2012/03/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/04

Citations

• Estimating Missing Heritability for Disease from Genome-wide Association Studies
• GCTA: A Tool for Genome-wide Complex Trait Analysis
• Hundreds of variants clustered in genomic loci and biological pathways affect human height
• Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
• Common SNPs explain a large proportion of the heritability for human height

Cited by

• Common DNA Markers Can Account for More Than Half of the Genetic Influence on Cognitive Abilities
• Research Review: Polygenic methods and their application to psychiatric traits
• Genes, behavior, and behavior genetics
• Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
• Uncovering the Hidden Risk Architecture of the Schizophrenias: Confirmation in Three Independent Genome-Wide Association Studies
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
• Behavioural genetics [wikipedia]
• Psychology [wikipedia]