Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2

2003/03/10 by Joseph R. Pomerening, Eduardo D. Sontag, James E. Ferrell · 8 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Biology #Bistability #Cell #Cell biology #Cell cycle #Chemistry #Cyclin #Cyclin A #Cyclin B #Cyclin B1 #Cyclin-dependent kinase 1 #Gene Regulatory Network Analysis #Genetics #Microtubule and mitosis dynamics #Mitosis #Optoelectronics #Physics #Plant Molecular Biology Research

paper · doi:10.1038/ncb954

crossref issued 2003/03/10 · crossref published 2003/03/10 · crossref published-online 2003/03/10 · openalex publication_date 2003/03/10 · crossref published-print 2003/04/01 · crossref created 2003/04/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/07/21 · openalex updated_date 2026/08/01

Citations

• Cyclin is degraded by the ubiquitin pathway
• Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes
• Mechanisms of noise-resistance in genetic oscillators
• Testing a Mathematical Model of the Yeast Cell Cycle

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• Coupled Reversible and Irreversible Bistable Switches Underlying TGFβ-induced Epithelial to Mesenchymal Transition
• Singularly Perturbed Monotone Systems and an Application to Double Phosphorylation Cycles
• Bistability: Requirements on Cell-Volume, Protein Diffusion, and Thermodynamics
• Hysteresis [wikipedia]