2012/10/01 by Robin A. Hurley, Katherine H. Taber · 1 citation
Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #HIV Research and Treatment #Herpesvirus Infections and Treatments #Toxoplasma gondii #Toxoplasmosis #Schizophrenia (object-oriented programming) #Population #Biology #Immunology #Medicine #Environmental health #Psychiatry #Antibody
paper · doi:10.1176/appi.neuropsych.12100234
openalex publication_date 2012/10/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/15
Toxoplasmosis gondii (T. gondii) an intracellular parasite discovered in 1908, is present in about one-third of the world’s population; once infected, hosts remain seropositive for life. (Known exposure risks are feline feces; raw or undercooked meat; raw oysters, clams, and mussels; and unwashed raw fruits and vegetables.) Various studies worldwide have found personality/adjustment difficulties, such as increased anxiety, in otherwise-healthy seropositive individuals, and seropositivity in schizophrenia patients was found to be almost three times that of a control population. Unlike the acute form, chronic latent T. gondii infection resides in intact neurons; and there is considerable variation in findings of structures affected, although there does appear to be a predilection for dopaminergic neurons.