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IMPACT OF TANDEM REPEATS ON THE SCALING OF NUCLEOTIDE SEQUENCES

2005/10/21 by Radhakrishnan Nagarajan, RADHAKRISHNAN NAGARAJAN, Meenakshi Upreti +1
Biochemistry, Genetics and Molecular Biology · Economics, Econometrics and Finance · Physics and Astronomy · #Complex Systems and Time Series Analysis #Exponent #Fractal and DNA sequence analysis #Microsatellite #Nucleotide #Scaling #Scaling law #Sequence (biology) #Tandem #Tandem repeat #Theoretical and Computational Physics #cond-mat.stat-mech #q-bio.GN

paper · pdf · doi:10.1142/s0218127406016690

14 Pages, 3 Figures

arxiv created 2005/10/21 · openalex publication_date 2006/10/01 · openalex created_date 2016/06/24 · arxiv updated 2016/12/21 · openalex updated_date 2026/08/05

Abstract

Techniques such as detrended fluctuation analysis (DFA) and its extensions have been widely used to determine the nature of scaling in nucleotide sequences. In this brief communication we show that tandem repeats which are ubiquitous in nucleotide sequences can prevent reliable estimation of possible long-range correlations. Therefore, it is important to investigate the presence of tandem repeats prior to scaling exponent estimation.

Citations