Vertical collapse of a cytolysin prepore moves its transmembrane β‐hairpins to the membrane

2004/08/05 by Daniel M. Czajkowsky, Daniel M Czajkowsky, Eileen M Hotze +4 · 7 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #Calcium signaling and nucleotide metabolism #Lipid Membrane Structure and Behavior #Nanopore and Nanochannel Transport Studies

paper · pdf · doi:10.1038/sj.emboj.7600350

crossref issued 2004/08/05 · crossref published 2004/08/05 · crossref published-online 2004/08/05 · openalex publication_date 2004/08/05 · crossref created 2004/08/05 · crossref published-print 2004/08/18 · openalex created_date 2025/10/10 · crossref deposited 2026/05/19 · crossref indexed 2026/06/01 · openalex updated_date 2026/08/01

Citations

• Structure of a Cholesterol-Binding, Thiol-Activated Cytolysin and a Model of Its Membrane Form
• Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming Toxin Clostridium perfringens Perfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy
• Monomer-Monomer Interactions Drive the Prepore to Pore Conversion of a β-Barrel-forming Cholesterol-dependent Cytolysin
• The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin
• Bacillus thuringiensis and Its Pesticidal Crystal Proteins
• Arresting Pore Formation of a Cholesterol-dependent Cytolysin by Disulfide Trapping Synchronizes the Insertion of the Transmembrane β-Sheet from a Prepore Intermediate

Cited by

• Characterization of a Streptococcal Cholesterol-Dependent Cytolysin with a Lewis y and b Specific Lectin Domain
• Cholesterol Exposure at the Membrane Surface Is Necessary and Sufficient to Trigger Perfringolysin O Binding
• Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy
• The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly
• The Cholesterol-Dependent Cytolysin Family of Gram-Positive Bacterial Toxins
• Monomer-Monomer Interactions Propagate Structural Transitions Necessary for Pore Formation by the Cholesterol-dependent Cytolysins
• Cholesterol-dependent cytolysin [wikipedia]