Inflammatory Bowel Disease

2002/08/08 by Daniel K. Podolsky · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Inflammatory Bowel Disease #Microscopic Colitis #Helicobacter pylori-related gastroenterology studies

paper · doi:10.1056/nejmra020831

openalex publication_date 2002/08/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Clinical experience has suggested that Crohn's disease and ulcerative colitis constitute distinct, if not discrete, entities. However, whether these conditions are fundamentally different or are part of a mechanistic continuum is a question with both conceptual and practical implications for management. This review summarizes current understanding of the mechanisms underlying the major forms of inflammatory bowel disease and discusses approaches to therapy.

Citations

• Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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