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Pyrimidine as Constituent of Natural Biologically Active Compounds

2005/01/01 by Irene M. Lagoja · 3 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Biochemical and Molecular Research #Origins and Evolution of Life #Chemical Synthesis and Analysis

paper · doi:10.1002/cbdv.200490173

openalex publication_date 2005/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

This review describes the various manifestations of the pyrimidine system (alkylated, glycosylated, benzo-annelated.). These comprise pyrimidine nucleosides as well as alkaloids and antibiotics--some of them have been discovered and isolated from natural sources already long time ago, others have been reported very recently. A short overview on pyrimidine syntheses (prebiotic synthesis, biosynthesis, and metabolism) is given. The biological activities of most of the pyrimidine analogs are briefly described, and, in some cases, syntheses are formulated.

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