2008/01/30 by Carlo M. Croce · 1 citation
Biochemistry, Genetics and Molecular Biology · #MicroRNA in disease regulation #RNA modifications and cancer #Cancer-related gene regulation
paper · doi:10.1056/nejmra072367
openalex publication_date 2008/01/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the treatment of cancer.