2001/08/10 by Robert A. Martienssen, Vincent Colot · 523 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #DNA methylation #Epigenetics #Epigenetics of physical exercise #Epigenomics #Gene #Gene expression #Genetics #Genome #Legume Nitrogen Fixing Symbiosis #Methylation #Plant Molecular Biology Research #Plant tissue culture and regeneration #RNA-Directed DNA Methylation #Transposable element
paper · doi:10.1126/science.293.5532.1070
published in Science 293(5532), 1070-1074 (American Association for the Advancement of Science)
openalex publication_date 2001/08/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. In these organisms, DNA methylation is associated with gene silencing and transposon control. However, plants and fungi differ from mammals in the genomic distribution, sequence specificity, and heritability of methylation. We consider the role that transposons play in establishing methylation patterns and the epigenetic consequences of their perturbation.