2008/11/07 by Shamith Samarajiwa, Samuel C. Forster, Katie Auchettl +1 · 1 citation
Immunology and Microbiology · Medicine · Biochemistry, Genetics and Molecular Biology · #interferon and immune responses #Cytokine Signaling Pathways and Interactions #Cancer-related molecular mechanisms research
paper · pdf · doi:10.1093/nar/gkn732
openalex publication_date 2008/11/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
INTERFEROME is an open access database of types I, II and III Interferon regulated genes (http://www.interferome.org) collected from analysing expression data sets of cells treated with IFNs. This database of interferon regulated genes integrates information from high-throughput experiments with annotation, ontology, orthologue sequences from 37 species, tissue expression patterns and gene regulatory information to enable a detailed investigation of the molecular mechanisms underlying IFN biology. INTERFEROME fulfils a need in infection, immunity, development and cancer research by providing computational tools to assist in identifying interferon signatures in gene lists generated by high-throughput expression technologies, and their potential molecular and biological consequences.