Restoration of p53 function leads to tumour regression in vivo

2007/01/24 by Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin +8 · 6 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Research and Treatments #Cancer-related Molecular Pathways #Epigenetics and DNA Methylation

paper · doi:10.1038/nature05541

crossref issued 2007/01/24 · crossref published 2007/01/24 · crossref published-online 2007/01/24 · openalex publication_date 2007/01/24 · crossref created 2007/01/24 · crossref published-print 2007/02/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/07/27 · openalex updated_date 2026/07/28

Citations

• Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
• The Hallmarks of Cancer

Cited by

• Awakening guardian angels: drugging the p53 pathway
• Targeting mutant p53 for efficient cancer therapy
• YPEL3, a p53-Regulated Gene that Induces Cellular Senescence
• Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females
• Experimental cancer treatment [wikipedia]
• P53 [wikipedia]