Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach

2000/06/01 by Shelley D. Copley, Shelley D Copley · 5 citations
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Glutathione Transferases and Polymorphisms #Microbial bioremediation and biosurfactants #Toxic Organic Pollutants Impact

paper · doi:10.1016/s0968-0004(00)01562-0

crossref issued 2000/06/01 · crossref published 2000/06/01 · crossref published-print 2000/06/01 · openalex publication_date 2000/06/01 · crossref created 2002/07/26 · crossref deposited 2020/02/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29 · crossref indexed 2026/08/05

Citations

• The Natural Production of Chlorinated Compounds
• Catalytic promiscuity and the evolution of new enzymatic activities
• ENZYME RECRUITMENT IN EVOLUTION OF NEW FUNCTION
• The puzzle of the Krebs citric acid cycle: Assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution

Cited by

• Biological design in science classrooms
• The recent evolution of pentachlorophenol (PCP)-4-monooxygenase (PcpB) and associated pathways for bacterial degradation of PCP
• Metabolites: a helping hand for pathway evolution?
• Small-molecule metabolism: an enzyme mosaic
• Evolution [wikipedia]