Exploring prokaryotic diversity in the genomic era.

2002/01/01 by Philip Hugenholtz · 5 citations
Biochemistry, Genetics and Molecular Biology · Environmental Science · Agricultural and Biological Sciences · #Genomics and Phylogenetic Studies #Microbial Community Ecology and Physiology #Probiotics and Fermented Foods

paper · pdf · doi:10.1186/gb-2002-3-2-reviews0003

openalex publication_date 2002/01/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/03

Abstract

Our understanding of prokaryote biology from study of pure cultures and genome sequencing has been limited by a pronounced sampling bias towards four bacterial phyla - Proteobacteria, Firmicutes, Actinobacteria and Bacteroidetes - out of 35 bacterial and 18 archaeal phylum-level lineages. This bias is beginning to be rectified by the use of phylogenetically directed isolation strategies and by directly accessing microbial genomes from environmental samples.

Citations

• Phylogenetic structure of the prokaryotic domain: The primary kingdoms
• Phylogenetic identification and in situ detection of individual microbial cells without cultivation
• Impact of Culture-Independent Studies on the Emerging Phylogenetic View of Bacterial Diversity
• Bacterial evolution

Cited by

• The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific
• Lateral Gene Transfer and the Origins of Prokaryotic Groups
• Bacterial Community in the Crop of the Hoatzin, a Neotropical Folivorous Flying Bird
• Exploring bacterial diversity via a curated and searchable snapshot of archived DNA sequences
• Cell wall [wikipedia]