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18FDG PET-CT in sporadic Creutzfeldt-Jakob disease, correlated with MRI and histology

2021/10/01 by Nicholas Morley, Monika Hofer, Philip Wilkinson +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Prion Diseases and Protein Misfolding

paper · pdf · doi:10.4103/wjnm.wjnm_5_21

openalex publication_date 2021/10/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/02

Abstract

We present a case of sporadic Creutzfeldt-Jakob disease with profoundly abnormal 18fluoro-deoxy-glucose positron emission tomography with computed tomography (FDG PET-CT) at an early stage, and correlate this with the clear findings at magnetic resonance imaging and also postmortem histology. Prion diseases are rare but important causes of cognitive impairment. The role of FDG PET-CT is discussed, along with other investigations such as electroencephalography and cerebro-spinal fluid analyses.

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