2013/01/27 by Tonya M. Atkins, Maja C. Cassidy, Menyoung Lee +3 · 75 citations
Chemistry · Engineering · Physics and Astronomy · #Advanced NMR Techniques and Applications #Amorphous silicon #Amorphous solid #Crystallography and Radiation Phenomena #Hyperpolarization (physics) #Magnetic nanoparticles #Muon and positron interactions and applications #Nanoparticle #Polarization (electrochemistry) #Silicon #cond-mat.mes-hall #cond-mat.mtrl-sci
paper · pdf · doi:10.1021/nn305462y
published in ACS Nano 7(2), 1609-1617 (American Chemical Society) · Supporting material: https://dl.dropboxusercontent.com/u/1742676/Supporting_Atkins_v11.pdf
openalex publication_date 2013/01/27 · arxiv created 2013/05/02 · arxiv updated 2014/01/14 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/05
We describe the synthesis, materials characterization, and dynamic nuclear polarization (DNP) of amorphous and crystalline silicon nanoparticles for use as hyperpolarized magnetic resonance imaging (MRI) agents. The particles were synthesized by means of a metathesis reaction between sodium silicide (Na₄Si₄) and silicon tetrachloride (SiCl₄) and were surface functionalized with a variety of passivating ligands. The synthesis scheme results in particles of diameter ∼10 nm with long size-adjusted ²⁹Si spin-lattice relaxation (T₁) times (>600 s), which are retained after hyperpolarization by low-temperature DNP.