A Co-Evolution Theory of the Genetic Code

1975/05/01 by J. Tze‐Fei Wong · 22 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Bacterial Genetics and Biotechnology #Origins and Evolution of Life #RNA and protein synthesis mechanisms

paper · doi:10.1073/pnas.72.5.1909

openalex publication_date 1975/05/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Abstract

The theory is proposed that the structure of the genetic code was determined by the sequence of evolutionary emergence of new amino acids within the primordial biochemical system.

Citations

• The origin of the genetic code

Cited by

• From chemical metabolism to life: the origin of the genetic coding process
• A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code
• The complex evolutionary history of aminoacyl-tRNA synthetases
• Early Fixation of an Optimal Genetic Code
• Role of minimization of chemical distances between amino acids in the evolution of the genetic code.
• Origin and evolution of the genetic code: The universal enigma
• The Case for an Error Minimizing Standard Genetic Code
• A colorful origin for the genetic code: Information theory, statistical mechanics and the emergence of molecular codes
• The Genetic Code Is One in a Million
• Selection, history and chemistry: the three faces of the genetic code
• The code within the codons
• Rhyme or reason: RNA-arginine interactions and the genetic code
• RNA–Amino Acid Binding: A Stereochemical Era for the Genetic Code
• Evolution of Amino Acid Frequencies in Proteins Over Deep Time: Inferred Order of Introduction of Amino Acids into the Genetic Code
• Testing a biosynthetic theory of the genetic code: Fact or artifact?
• What can information-asymmetric games tell us about the context of Crick's ‘frozen accident’?
• Pathways of Genetic Code Evolution in Ancient and Modern Organisms
• The extension reached by the minimization of the polarity distances during the evolution of the genetic code
• The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited
• A model for the emergence of the genetic code as a transition in a noisy information channel
• The origin of the genetic code: amino acids as cofactors in an RNA world
• Amino acid [wikipedia]