2020/07/30 by D. Leimbach, J. Karls, Yangyang Guo +35 · 1 citation
Medicine · Physics and Astronomy · #Radiopharmaceutical Chemistry and Applications #Advanced Chemical Physics Studies #Atomic and Molecular Physics
paper · pdf · doi:10.1038/s41467-020-17599-2
openalex publication_date 2020/07/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
Abstract One of the most important properties influencing the chemical behavior of an element is the electron affinity (EA). Among the remaining elements with unknown EA is astatine, where one of its isotopes, 211 At, is remarkably well suited for targeted radionuclide therapy of cancer. With the At − anion being involved in many aspects of current astatine labeling protocols, the knowledge of the electron affinity of this element is of prime importance. Here we report the measured value of the EA of astatine to be 2.41578(7) eV. This result is compared to state-of-the-art relativistic quantum mechanical calculations that incorporate both the Breit and the quantum electrodynamics (QED) corrections and the electron–electron correlation effects on the highest level that can be currently achieved for many-electron systems. The developed technique of laser-photodetachment spectroscopy of radioisotopes opens the path for future EA measurements of other radioelements such as polonium, and eventually super-heavy elements.