2009/12/16 by Julie Champion, Cyrille Alliot, Éric Renault +4 · 6 citations
Physics and Astronomy · Medicine · #Advanced Chemical Physics Studies #Metal complexes synthesis and properties #Radiopharmaceutical Chemistry and Applications
paper · doi:10.1021/jp9077008
openalex publication_date 2009/12/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22
A combined experimental and theoretical approach is used to define astatine (At) speciation in acidic aqueous solution and to answer the two main questions raised from literature data: does At(0) exist in aqueous solution and what is the chemical form of At(+III), if it exists. The experimental approach considers that a given species is characterized by its distribution coefficient (D) experimentally determined in a biphasic system. The change in speciation arising from a change in experimental conditions is observed by a change in D value. The theoretical approach involves quasi-relativistic quantum chemistry calculations. The results show that At at the oxidation state 0 cannot exist in aqueous solution. The three oxidation states present in the range of water stability are At(-I), At(+I), and At(+III) and exist as At(-), At(+), and AtO(+), respectively, in the 1-2 pH range. The standard redox potentials of the At(+)/At(-) and AtO(+)/At(+) couples have been determined, the respective values being 0.36 +/- 0.01 and 0.74 +/- 0.01 V vs NHE.