2010/10/31 by Jens Ehrig, Eugene P. Petrov, Petra Schwille · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #Electrostatics and Colloid Interactions #Lipid Membrane Structure and Behavior #Nanopore and Nanochannel Transport Studies #cond-mat.soft #physics.bio-ph
paper · pdf · doi:10.1016/j.bpj.2010.11.002
published as Biophysical Journal 100 (2011) 80 · 21 pages, 5 figures; Supporting Material 5 pages, 1 figure, 1 table
arxiv created 2010/11/23 · openalex publication_date 2011/01/01 · arxiv updated 2011/04/29 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We address the relationship between membrane microheterogeneity and anomalous subdiffusion in cell membranes by carrying out Monte Carlo simulations of two-component lipid membranes. We find that near-critical fluctuations in the membrane lead to transient subdiffusion, while membrane-cytoskeleton interaction strongly affects phase separation, enhances subdiffusion, and eventually leads to hop diffusion of lipids. Thus, we present a minimum realistic model for membrane rafts showing the features of both microscopic phase separation and subdiffusion.