2010/08/13 by Kaifu Luo, Ralf Metzler
Chemistry · Engineering · Mathematics · Physics and Astronomy · #Biology #Biophysics #Cav1.2 #Channel (broadcasting) #Chemical physics #Chemistry #Chromosomal translocation #Computer science #Electrical engineering #Electrostatics and Colloid Interactions #Exponent #Fluidics #Geometry #Inverse #Ion-surface interactions and analysis #Langevin dynamics #Materials science #Mathematics #Molecular dynamics #Nanopore #Nanopore and Nanochannel Transport Studies #Nanotechnology #Nuclear magnetic resonance #Physics #Polymer #Quantum mechanics #Scaling #Statistical physics #cond-mat.soft
paper · pdf · doi:10.1103/physreve.82.021922
published as Phys. Rev. E 82, 021922 (2010) · 8 pages, 12 figures. To appear in Phys. Rev. E
arxiv created 2010/08/13 · openalex publication_date 2010/08/27 · arxiv updated 2010/08/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Using two-dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter R through a nanopore under a driving force F . Due to the crowding effect induced by the partially translocated monomers, the translocation dynamics is significantly altered in comparison to an unconfined environment, namely, we observe a nonuniversal dependence of the translocation time τ on the chain length N . τ initially decreases rapidly and then saturates with increasing R , and a dependence of the scaling exponent α of τ with N on the channel width R is observed. The otherwise inverse linear scaling of τ with F breaks down and we observe a minimum of α as a function of F . These behaviors are interpreted in terms of the waiting time of an individual segment passing through the pore during translocation.