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Catalytic Transfer Functionalization through Shuttle Catalysis

2016/09/26 by Benjamin N. Bhawal, Bill Morandi · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemical Engineering · Chemistry · #Asymmetric Hydrogenation and Catalysis #Carbon dioxide utilization in catalysis #Chemical Synthesis and Analysis

paper · doi:10.1021/acscatal.6b02333

openalex publication_date 2016/09/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Abstract

In this Perspective, we describe an emerging type of catalysis that enables the catalytic reversible transfer of chemical entities beyond the well-established transfer hydrogenation reactions. Shuttle catalysis facilitates the transfer of small molecules (e.g., CO, HCN) or reactive intermediates between two substrates in an isodesmic process. In many cases, these often safer processes provide unprecedented synthetic flexibility and complement other catalytic bond-forming and bond-breaking reactions.

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