2008/01/07 by Xihua Wang, Yu Chen, Katherine A. Gibney +2
Engineering · Materials Science · Physics and Astronomy · #Electrochemical sensors and biosensors #Nanopore and Nanochannel Transport Studies #Silicon Nanostructures and Photoluminescence #cond-mat.other #physics.bio-ph #physics.chem-ph
paper · pdf · doi:10.1063/1.2832648
published as Appl. Phys. Lett. 92, 013903 (2008) · 3 pages, 3 figures, two-column format. Related papers can be found at http://nano.bu.edu
openalex publication_date 2008/01/07 · arxiv created 2008/02/12 · arxiv updated 2009/12/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The differential conductance of silicon nanowires, tuned with source-drain bias voltage, is demonstrated to be sensitive to the biocatalyzed oxidation of glucose. The glucose biosensor response is linear in the 0.5–8mM concentration range with 3–5min response time. This silicon nanochannel-based glucose biosensor technology offers the possibility of high density, high quality glucose biosensor integration with silicon-based circuitry.