Highly Efficient Ruthenium Catalysts for the Formation of Tetrasubstituted Olefins via Ring-Closing Metathesis

2007/03/23 by Ian C. Stewart, Thay Ung, Alexandre A. Pletnev +3 · 2 citations
Chemistry · Biochemistry, Genetics and Molecular Biology · Engineering · #Synthetic Organic Chemistry Methods #Chemical Synthesis and Analysis #Fuel Cells and Related Materials

paper · doi:10.1021/ol0705144

openalex publication_date 2007/03/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

[reaction: see text] A series of ruthenium-based metathesis catalysts with N-heterocyclic carbene (NHC) ligands have been prepared in which the N-aryl groups have been changed from mesityl to mono-ortho-substituted phenyl (e.g., tolyl). These new catalysts offer an exceptional increase in activity for the formation of tetrasubstituted olefins via ring-closing metathesis (RCM), while maintaining high levels of activity in ring-closing metathesis (RCM) reactions that generate di- and trisubstituted olefins.

Citations

• Multiple Metal–Carbon Bonds for Catalytic Metathesis Reactions (Nobel Lecture)
• The Development of L2X2RuCHR Olefin Metathesis Catalysts: An Organometallic Success Story
• Olefin‐Metathesis Catalysts for the Preparation of Molecules and Materials (Nobel Lecture)

Cited by

• Nonproductive Events in Ring-Closing Metathesis Using Ruthenium Catalysts
• Ring-closing metathesis [wikipedia]